Continue Reading... Hexavalent Chromium-Induced Chromosome Instability Drives Permanent and Heritable Numerical and Structural Changes and a DNA Repair-Deficient Phenotype
Posted in Health Sciences

Hexavalent Chromium-Induced Chromosome Instability Drives Permanent and Heritable Numerical and Structural Changes and a DNA Repair-Deficient Phenotype

NIEHS intramural scientists have defined descriptive terms of particular relevance to their own research, and have ranked those terms accordingly….

Continue Reading... Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-Induced Proliferation In Mouse Liver
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Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-Induced Proliferation In Mouse Liver

NIEHS intramural scientists have defined descriptive terms of particular relevance to their own research, and have ranked those terms accordingly….

Continue Reading... Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity
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Toll-like Receptor 4 Pathway Polymorphisms Interact with Pollution to Influence Asthma Diagnosis and Severity

NIEHS intramural scientists have defined descriptive terms of particular relevance to their own research, and have ranked those terms accordingly….

Continue Reading... Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study
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Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study

Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study  [Abstract]  [Synopsis] Wang W, Moroi…

Continue Reading... Assessment of the DNA Damaging Potential of Environmental Chemicals Using a Quantitative High-Throughput Screening Approach to Measure p53 Activation
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Assessment of the DNA Damaging Potential of Environmental Chemicals Using a Quantitative High-Throughput Screening Approach to Measure p53 Activation

Assessment of the DNA Damaging Potential of Environmental Chemicals Using a Quantitative High-Throughput Screening Approach to Measure p53 Activation  [Abstract]…

Continue Reading... Estimated Exposures to Perfluorinated Compounds in Infancy Predict Attenuated Vaccine Antibody Concentrations at Age 5-Years
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Estimated Exposures to Perfluorinated Compounds in Infancy Predict Attenuated Vaccine Antibody Concentrations at Age 5-Years

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Continue Reading... Histologic and Biochemical Alterations Predict Pulmonary Mechanical Dysfunction in Aging Mice with Chronic Lung Inflammation
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Histologic and Biochemical Alterations Predict Pulmonary Mechanical Dysfunction in Aging Mice with Chronic Lung Inflammation

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Continue Reading... Time-Lapse Crystallography Snapshots of a Double-Strand Break Repair Polymerase in Action
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Time-Lapse Crystallography Snapshots of a Double-Strand Break Repair Polymerase in Action

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Continue Reading... Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization
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Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization

Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization  [Abstract]  [Synopsis] Carignan CC,…

Continue Reading... Evaluation of the Respiratory Tract Toxicity of Ortho-Phthalaldehyde, a Proposed Alternative For the Chemical Disinfectant Glutaraldehyde
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Evaluation of the Respiratory Tract Toxicity of Ortho-Phthalaldehyde, a Proposed Alternative For the Chemical Disinfectant Glutaraldehyde

Evaluation of the Respiratory Tract Toxicity of Ortho-Phthalaldehyde, a Proposed Alternative For the Chemical Disinfectant Glutaraldehyde  [Abstract]  [Synopsis] Catlin NR,…

Continue Reading... Chromosomal Landscape of UV Damage Formation and Repair at Single-Nucleotide Resolution
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Chromosomal Landscape of UV Damage Formation and Repair at Single-Nucleotide Resolution

https://www.ncbi.nlm.nih.gov/pubmed/27457959

Continue Reading... Maternal Folate Intake During Pregnancy and Childhood Asthma in a Population Based Cohort
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Maternal Folate Intake During Pregnancy and Childhood Asthma in a Population Based Cohort

Maternal Folate Intake During Pregnancy and Childhood Asthma in a Population Based Cohort  [Abstract]  [Synopsis] Parr CL, Magnus MC, Karlstad…

Continue Reading... Soy Formula and Epigenetic Modifications: Analysis of Vaginal Epithelial Cells from Infant Girls in the IFED Study
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Soy Formula and Epigenetic Modifications: Analysis of Vaginal Epithelial Cells from Infant Girls in the IFED Study

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Continue Reading... Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditis elegans
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Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditis elegans

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Continue Reading... p62, Upregulated During Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-initiating Cells
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p62, Upregulated During Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-initiating Cells

p62, Upregulated During Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-initiating Cells  [Abstract]  [Synopsis] Umemura A, He F,…

Continue Reading... DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking During Pregnancy
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DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking During Pregnancy

DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking During Pregnancy  [Abstract]  [Synopsis] Reese SE, Zhao S,…

Continue Reading... Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons
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Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons

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Continue Reading... Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal
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Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal

Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt…

Continue Reading... Regulator of G-Protein Signaling 2 (RGS2) Suppresses Premature Calcium Release in Mouse Eggs
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Regulator of G-Protein Signaling 2 (RGS2) Suppresses Premature Calcium Release in Mouse Eggs

Regulator of G-Protein Signaling 2 (RGS2) Suppresses Premature Calcium Release in Mouse Eggs  [Abstract]  [Synopsis]  [Story] Bernhardt ML, Lowther KM,…

Continue Reading... Association of Exposure to Di-2-Ethylhexyphthalate Replacements With Increased Blood Pressure in Children and Adolescents
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Association of Exposure to Di-2-Ethylhexyphthalate Replacements With Increased Blood Pressure in Children and Adolescents

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Continue Reading... Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the U.S.
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Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the U.S.

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Continue Reading... An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A
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An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A

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Continue Reading... Effects of In Utero Exposure To Arsenic During the Second Half of Gestation on Reproductive End Points and Metabolic Parameters in Female CD-1 Mice
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Effects of In Utero Exposure To Arsenic During the Second Half of Gestation on Reproductive End Points and Metabolic Parameters in Female CD-1 Mice

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Continue Reading... Current and Projected Heat-Related Morbidity and Mortality in Rhode Island
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Current and Projected Heat-Related Morbidity and Mortality in Rhode Island

Current and Projected Heat-Related Morbidity and Mortality in Rhode Island  [Abstract]  [Synopsis] Kingsley SL, Eliot MN, Gold J, Vanderslice RR,…

Continue Reading... Creative Template-Dependent Synthesis by Human Polymerase Mu
Posted in Health Sciences

Creative Template-Dependent Synthesis by Human Polymerase Mu

https://www.ncbi.nlm.nih.gov/pubmed/26240373

Continue Reading... Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice
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Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice

Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice  [Abstract]  [Synopsis] Bhusari S, Pandiri…

Continue Reading... Base Triplet Stepping by the Rad51/RecA Family of Recombinases
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Base Triplet Stepping by the Rad51/RecA Family of Recombinases

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Continue Reading... Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS
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Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS

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Continue Reading... Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004
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Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004

Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004  [Abstract]  [Synopsis] Dinse GE,…

Continue Reading... Season and Preterm Birth in Norway: A Cautionary Tale
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Season and Preterm Birth in Norway: A Cautionary Tale

https://www.ncbi.nlm.nih.gov/pubmed/26045507